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[Preprint]. 2024 Apr 23:2024.04.22.24306094. [Version 1] doi: 10.1101/2024.04.22.24306094

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Figure 1. — A) Overview of study design and sample sizes. To increase specificity to AD (rather than ADD), the XWAS meta-analysis was intersected to variants with association results in ADGC (which used only clinically confirmed cases and controls). B) Manhattan plot for the XWAS meta-analysis. The dotted line indicates X-chromosome-wide significance (P-value<1e-5) and full line indicates genome-wide significance (P-value<5e-8). Lead variants for independent loci are annotated with their nearest protein-coding gene (Gencode v42).