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[Preprint]. 2024 Apr 27:2024.04.25.24306377. [Version 1] doi: 10.1101/2024.04.25.24306377

Figure 2:

Figure 2:

Cross-ancestry polygenic score model comparison for psychiatric phenotypes

Comparison of European-GWAS derived PGS predictive accuracy for BD, OCD, and externalizing traits in an Indian cohort using PRSice-2, PGS-CS-auto, and SBayesRC. Imputed data shows enhanced prediction, with Bayesian methods outperforming PRSice-2 in cross-ancestry application.