Figure 2.

Correlation between cell type frequencies and clinical information. (A) Bar plots showing Pearson’s correlation coefficients between the frequencies of 11 cell types and disease severity scores (MGC and MG-ADL) and the 15-item MG-QOL. (B) Bar plots showing Pearson’s correlation coefficients between the degrees of disease alleviation through intravenous immunoglobulin (IVIg) administration in patients with seronegative (SN) myasthenia gravis (MG) and the frequency of changes in each cell type. (C) Scatter plots with a particularly significant correlation between the frequency of cell type and disease severity score in MG patients. (D) Scatter plots with a particularly significant correlation between the degrees of disease alleviation by IVIg treatment in patients with SN MG and the frequency changes. The blue line indicates the regression line, and the gray zone indicates the 95% confidence interval. DC, dendritic cell; pDC, plasmacytoid DC; Treg, regulatory T cell; NK, natural killer cell; MGC, MG composite scale; MG-ADL, MG-Activities of Daily Living.