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. 2024 Apr 22;15:1382320. doi: 10.3389/fimmu.2024.1382320

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Copyright © 2024 Okuzono, Miyakawa, Itou, Sagara, Iwata, Ishizuchi, Sekiguchi, Motegi, Oyama, Warude, Kikukawa and Suzuki

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vitro assays for the comparison of regulatory T cell (Treg) functions in each group. (A) Box plots showing the proliferation rate as fold changes of cell counts between pre- and post-expansion for each group. Numerical values show the median for each group (P value is not stated because there were no statistically significant differences). (B) Sigmoid curve plots showing Treg-suppressive functions measured based on the inhibition rate of cell division of CD4T cells co-cultured with Tregs. Error bars indicate the standard deviation (P value is not stated because there were no statistically significant differences). MG, myasthenia gravis; HC, healthy control; AChR+, acetylcholine receptor-positive; SN, seronegative.