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. 2024 Apr 15;5(1):zpae023. doi: 10.1093/sleepadvances/zpae023

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© The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Relationship of the midpoint of sleep and NREM slow-wave activity. Rounded to the nearest minute, the midpoint of sleep was separated into quantiles of 11:46 pm to 02:07 am (first, leftmost), 02:07 am to 02:38 am (second), 02:38 am to 03:03 am (third), 03:03 am to 03:28 am (fourth), 03:28 am to 03:55 am (fifth), 03:55 am to 10:04 am (sixth, rightmost). < 1 Hz and 1–2 Hz NREM slow-wave activity (SWA) increased with later midpoint of sleep (A, B). The same relationship was not seen for 2–3 Hz NREM SWA (C) or 3–4 Hz (D).