Table 2.

Pro-apoptotic vs anti-apoptotic roles of DUBs

DUBs	Roles	References
A20	Anti-apoptotic	[90–92]
CYLD	Pro-apoptotic	[34, 36–40]
FAM188B	Anti-apoptotic	[93]
JOSD1	Anti-apoptotic	[94, 97, 98]
OTUB1	Pro-apoptotic	[49, 50]
	Anti-apoptotic	[99]
PPPDE1	Anti-apoptotic	[100, 101]
UCHL1	Pro-apoptotic	[52, 53]
	Anti-apoptotic	[180, 181]
UCHL5/UCH37	Pro-apoptotic	[54, 55]
	Anti-apoptotic	[78, 103]
USP1	Anti-apoptotic	[105, 106]
USP2	Pro-apoptotic	[56–58]
	Anti-apoptotic	[107–109]
USP4	Pro-apoptotic	[61, 62]
	Anti-apoptotic	[111–113]
USP5	Anti-apoptotic	[114–119]
USP7	Pro-apoptotic	[65, 66]
	Anti-apoptotic	[121, 122]
USP8	Anti-apoptotic	[123, 124]
USP9X	Pro-apoptotic	[67–70]
	Anti-apoptotic	[127–129]
USP10	Pro-apoptotic	[71, 73, 76]
	Anti-apoptotic	[72, 130]
USP11	Anti-apoptotic	[131, 132]
USP13	Anti-apoptotic	[125]
USP14	Pro-apoptotic	[78]
	Anti-apoptotic	[140]
USP15	Anti-apoptotic	[144–146]
USP18	Anti-apoptotic	[148, 149]
USP21	Anti-apoptotic	[152–154]
USP22	Anti-apoptotic	[155–159]
USP24	Pro-apoptotic	[79]
USP28	Pro-apoptotic	[80–84]
USP30	Pro-apoptotic	[85–87]
USP33	Pro-apoptotic	[88]
USP51	Anti-apoptotic	[160, 161]