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. 2021 Apr 15;78(10):4589–4613. doi: 10.1007/s00018-021-03801-1

Fig. 3.

Fig. 3

The Ku heterodimer functions in various cellular processes and interacts with multiple proteins. Figure adapted from Downs and Jackson (2004) [147] review. A selection of well-characterized cellular functions that have been shown to involve Ku, including key human Ku protein/RNA interactors