Fig. 7.

Common miRNAs regulating CHGA and cholesterol homeostatic genes. A Predicted and experimentally validated targets of miR-22 and miR-107 which are involved in cholesterol homeostasis. The genes enclosed in dotted-lined boxes indicate that they are predicted targets of the miRNA(s). B Potential regulation of CHGA by miRNAs which govern cholesterol homeostasis and their regulators. Red lines indicate repression, blue lines indicate activation and dotted lines indicate putative interactions obtained from in silico predictions