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. 2022 Aug 12;79(9):481. doi: 10.1007/s00018-022-04474-0

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© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 3 — Hypermethylated m⁵C in BL and LDM strongly relate to fatness/growth-related phenotypes. A PCA analysis of m⁵C in BL and LDM from Y and YJ. B Bar plot showing the result of KEGG pathway analysis of m⁵C-modified mRNAs in BL and LDM (all m⁵C-modified mRNAs combined from Y, YJ and J). C Heatmap and cluster analysis of differentially m⁵C-modified sites (|Y-J|> 0.05) in BL and LDM from Y, YJ, and J. D Bar plot showing the result of KEGG pathway analysis of mRNAs with hypermethylation in BL and LDM of Y compared with J. E Cumulative distribution analysis of the expression level changes in mRNAs with or without m⁵C modification