Fig. 5.

BTX-A reduced IMQ-induced psoriasiform dermatitis. a After NS or BTX-A injection, the phenotype of mice on the 0th, 3rd, and 6th days of IMQ application. b Skin thickness on the back skin. c PASI score from day 0 to day 6. P value compared NS + IMQ group with BTX-A + IMQ group. d HE staining of back skin, scale bar = 100 μm. e The statistics of epidermal thickness (μm) in HE staining, measured by NDP.view software. f IF of PGP9.5, scale bar = 100 μm. g The secretion concentration of CGRP in the skin tissue of mice on the 3rd day of modeling. h IF of βIII-tubulin and CGRP in DRG, scale bar = 100 μm. **P < 0.01, ***P < 0.0001, one-way ANOVA