Fig. 2.

Effects of long non-coding RNAs on chromatin remodeling complexes. LncRNAs (in blue) affect chromatin remodeling by changing subunit expression (transcription and/or competing for miRNA binding (ceRNAs)), by inhibiting complex binding to or by stimulating the recruitment to a genomic region. a Interaction of SWI/SNF complexes with lncRNA results in nucleosome sliding either further apart or closer together. b Histone replacement (H2A.Z) and modifications in nucleosomes are affected by lncRNAs that regulate the INO80 complexes. c LncRNAs known to regulate the different ISWI complexes are mainly recruiting these complexes. d Generally, lncRNAs that function as ceRNAs are known for the CHD family