Table 4.
Type of system | Split-Cas9 | Light-inducible | Destabilizing domain | NS3 domain | ||
---|---|---|---|---|---|---|
Intein-inducible | Rapamycin-inducible | Photoactivatable | ||||
In vivo studies | [259] | n/a | n/a | [178] | [260] | n/a |
Delivery vehicle | Viral-based delivery: AAV | n/a | n/a | DNA-based delivery: electroporation | DNA-based delivery: tail vein hydrodynamic injection | n/a |