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LP-184 IC50 in LMS cell lines. IC50 was calculated from 72-hour cell viability assay. PTGR1 RNA expression was retrieved from the DepMap Public 23Q2 Primary Files. HR activity of these cell lines was reported in ref. 34
| Cell Line | LP-184 IC50 (nmol/L) | PTGR1 RNA expression (log2TPM+1) | HR activity |
|---|---|---|---|
| SK-UT-1B | 45 | NA | Low |
| SK-LMS-1 | 135 | 6.7 | Low |
| SK-UT-1 | 173 | 5.8 | Low |
| MES-SA | >3,000 | 1.02 | NA |
