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. 2023 May 19;80(6):155. doi: 10.1007/s00018-023-04807-7

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Fig. 8 — The AKG diet alters the microbial metabolites in AAV-hα-Syn mice. a and b OPLS-DA plot and volcano plot showing the differential metabolites between AAV-hα-Syn and AAV-GFP. n = 6 per group. c The expression pattern of differential metabolites between AAV-hα-Syn and AAV-GFP. d and e OPLS-DA plot and volcano plot showing the differential metabolites between AAV-hα-Syn + AKG and AAV-hα-Syn. n = 6 per group. f The metabolomic class enriched by the differential metabolites between AAV-hα-Syn and AAV-GFP, AAV-hα-Syn + AKG and AAV-hα-Syn. g The expression pattern of differential metabolites among AAV-GFP, AAV-hα-Syn, and AAV-hα-Syn + AKG. h Hierarchical clustering of differential metabolites between AAV-hα-Syn + AKG and AAV-hα-Syn. i KEGG pathway enriched by these differential metabolites in (h). “Linoleic Acid Metabolism” and “Alpha Linolenic Acid metabolism” are highlighted