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. 2021 Jul 1;78(15):5755–5773. doi: 10.1007/s00018-021-03884-w

Fig. 3.

Fig. 3

Mechanisms of cortical expansion. During bone growth there are multiple processes that determine bone width: A radial expansion at the epiphyseal growth plate increases bone width, B periosteal resorption by osteoclasts at the metaphysis narrow the bone to fit the wide growth plate to the narrower diaphysis, and C osteoblast-mediated periosteal bone formation at the diaphysis