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. 2021 Nov 3;78(24):7967–7989. doi: 10.1007/s00018-021-04008-0

Fig. 1.

Fig. 1

The structural organization of SARS-CoV-2 genome. (A) Schematic representation of SARS-CoV-2 genome organization where, bp: base pair; ORF: Open reading frame; S: Spike protein; E: Envelope protein; M: Membrane protein; N: Nucleocapsid protein. (B) The structural features of SARS-CoV-2 (C) S1 and S2 subunits of SARS-CoV-2 S protein. (C) Block representation of SARS-CoV-2 S protein with its different domains namely, NTD, N-terminal domain; RBD, receptor-binding domain; FP, fusion peptide; HR1, heptad repeat 1, HR2, heptad repeat 2; TM, transmembrane domain; CT, cytoplasmic domain