Table 1.
Clinical trials assessing drug efficacy in obese (BMI ≥ 30 kg/m2) cancer patients
| Cancer | Drug | Study summary | Sex | Trial number |
|---|---|---|---|---|
| Multiple, advanced | Xeloda (Capecitabine) | Capecitabine pharmacokinetics in patients dosed as per ideal vs actual body weight | A | NCT01828554 |
| Colorectal | Metformin | Assessment of metformin in reduction of pS6Serine235 expression on mucosal tissue | A | NCT01312467 |
| Breast cancer | Doxorubicin, Cyclophosphamide | Assessment of drug plasma clearance between normal weight and obese patients | F | NCT01537029 |
| Endometrial cancer | Metformin | Assessment of effects of metformin administration prior to hysterectomy | F | NCT01877564 |