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. Author manuscript; available in PMC: 2024 May 6.
Published in final edited form as: Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966

Fig. 2: Deletion of Asters reduces cholesterol internalization from the plasma membrane.

Fig. 2:

(A) Backscattered electron images and NanoSIMS images of a mid-duodenum villus from WT and B/C KO mice. (B) Quantification of the 2H secondary ion signal, normalized to the 1H, 13C, and 16O signals. (C) ALOD4 imaging of murine enteroids from WT and B/C KO mice 2 h after loading with MβCD cholesterol For left panels, scale bar is 20 μm. For middle and right panels scale bar is 10 μm. Data are expressed as mean ± SEM. Statistical analysis: unpaired t test; *p < 0.05, ***p < 0.001, ****p < 0.0001.