Skip to main content
. 2024 Apr 24;20(4):e1011800. doi: 10.1371/journal.pcbi.1011800

Fig 17. Simulation of a system that exhibits stochastic switching between multiple steady states.

Fig 17

Copy numbers of unphosphorylated kinase A and its phosphorylated variant Ap are shown for a single simulation run in: A) MCell4; B) MCell3; and C) NFsim. The NFsim model was obtained by automatically exporting the MCell4 model into BNGL. The graphs also show solutions obtained with a deterministic ODE model for which data from [41] were used. The results demonstrate that the MCell results correctly reach one of the stable steady states shown in the ODE results. The simulation stays in such a state, and then due to stochastic behavior, a switch another steady state occurs.