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. 2024 Mar 28;38(5):1072–1080. doi: 10.1038/s41375-024-02204-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A overall survival for patient with central nervous system (CNS) and/or extramedullary (EM) involvement compared to patients without CNS and extramedullary involvement; B Overall survival for patient with de novo blast phase (CML-BP) and blast phase evolving from a previous chronic phase (CML-CP); C overall survival according to disease phenotype (myeloid vs. lymphoid); D overall survival according to disease phase (de novo) and ELTS score at the time of chronic phase (ELTS low, ELTS intermediate, ELTS high) [low ELTS vs. de novo HR 1.09 [95% CI: 0.68–1.75], p = 0.713, low ELTS vs. intermediate ELTS HR 2.35 [95% CI 1.35–4.11], p = 0.003, low ELTS vs. high ELTS HR 2.75 [95% CI: 1.57–4.81], p < 0.001]. All p values have to be interpreted as exploratory.