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. 2023 Dec 30;47(2):678–695. doi: 10.1007/s10753-023-01937-9

Table 2.

KEGG and GO Enrichment Terms Associated with the Hub Modules of DEGs

Module Nodes Edges KEGG enrichment GO enrichment
Up DEGs-1 58 821 Mitochondrial translation; mitochondrial translational termination; DNA replication Mitochondrial translation; Mitochondrial translational termination; mitochondrial translational elongation
Up DEGs-2 56 598 Oxidative phosphorylation; Ribosome; Parkinson’s disease Oxidative phosphorylation; Ribosome biogenesis; ATP metabolic process
Up DEGs-3 12 59 Spliceosome; Proteasome; RNA transport RNA splicing; mRNA processing; mRNA transport
Down DEGs-1 12 55 Melanogenesis; Tyrosine Pigmentation; developmental pigmentation; melanocyte differentiation

KEGG Kyoto Encyclopedia of Genes and Genomes, GO Gene Ontology, DEGs differentially expressed genes