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. 2024 May 6;15:3776. doi: 10.1038/s41467-024-47802-7

Table 1.

Bivariate GREML estimates of variance components between the (within-person) mean and two measures of within-person variability

Trait hSNP2 rg s.e. P
mean s.e. variability  s.e. P-value
A. Within-person trait mean and (absolute) trait deviation
height 0.527 0.008 0.024 0.007 2.0 × 10−4 0.094 0.053 0.081
BMI 0.256 0.008 0.054 0.007 8.8 × 10−15 0.872 0.052 1.1×10−63
weight 0.284 0.008 0.053 0.007 2.6 × 10−14 0.799 0.050 1.4×10−56
body fat % 0.242 0.008 0.000 0.007 0.966
waist cir. 0.226 0.008 0.011 0.006 0.103
hip cir. 0.246 0.008 0.009 0.006 0.157
waist:hip 0.200 0.008 0.000 0.006 0.969
sitting height 0.456 0.008 0.020 0.007 2.4×10−3 0.078 0.063 0.213
B. Within-person trait mean and rate of trait change
height 0.524 0.008 0.015 0.006 0.023 −0.130 0.072 0.072
BMI 0.254 0.008 0.035 0.007 3.4×10−7 0.163 0.059 0.006
weight 0.284 0.008 0.031 0.007 3.0×10−6 0.089 0.059 0.129
sitting height 0.452 0.008 0.010 0.006 0.125

Within-person variability was assessed with either A. the non-direction (absolute) trait deviation or B. the age- and sex- adjusted rate of trait change for 2 repeated measures of up to 8 anthropometric traits. Variance components are the SNP-based heritability (hSNP2) and genetic correlation (rg) between the mean and the measure of variability, where genetic correlations are reported only when hSNP2 of both traits significantly greater than zero (P < 0.05). Estimates are shown with standard errors (s.e.), and chi-squared tests (with 1 df) were used to calculated unadjusted P values.