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. 2024 Apr 23;14:1380599. doi: 10.3389/fonc.2024.1380599

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Copyright © 2024 Ling, Alexander, Molitoris, Choi, Schumaker, Tran, Mehra, Gaykalova and Ren

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Axial contrast-enhanced CT image of the oral cavity with a red region of interest (ROI) indicating the squamous cell carcinoma. The images were filtered by Laplacian of Gaussian (LoG) and analyzed to extract LDE and LRE features.