Table 3.

Comparison of patient outcomes in groups with perioperative dexamethasone use and without perioperative dexamethasone (using Fisher’s exact test (two-sided) and independent t-test).

Outcome	Dexamethasone use (72/148; 48.6%)	No dexamethasone use (76/148; 51.4%)	p-value
Immediate postoperative complications Venous thrombosis/pulmonary embolism New-Onset Seizures Stroke Wound infections Worsening or new motor, sensory, or brain nerve deficits	1 (1.4%) 11 (15.3%) 2 (2.8%) 3 (4.2%) 9 (12.5%)	1 (1.3%) 10 (13.2%) 1 (1.3%) 5 (6.6%) 6 (7.9%)	0.99 0.82 0.61 0.72 0.42
In-hospital mortality	1 (1.4%)	0 (0.0%)	0.49
New-onset hyperglycemia	3 (4.2%)	0 (0.0%)	0.11
Length of stay, days, mean ± SD	8.6 ± 3.9	7.2 ± 4.7	0.06
Reduction of extent of peritumoral T2-/FLAIR Hyperintensity (baseline vs. last follow-up MRI), cm, mean ± SD	1.8 ± 1.5	1.1 ± 0.9	0.04
Change in KPS, baseline - 3 months, mean ± SD	3.8 ± 9.8	-2.1 ± 9.9	0.001
Change in KPS, baseline - 12 months, mean ± SD	4.3 ± 8.3	-1.1 ± 9.6	0.004

P-values in italic represent statistically significant results.

KPS, Karnofsky Performance Status; SD, Standard deviation.