Table 2.
Neurological examination and clinical phenotypes in patients with inflammatory myopathy with mitochondrial pathology (IM-Mito) and inclusion body myositis (IBM).
| Features | IM-Mito, N = 14 a | IBM, N = 10 a | p value b |
|---|---|---|---|
| Finger flexor muscle weakness | 5 (35.7%) | 9 (90.0%) | 0.013 |
| Quadriceps muscle weakness | 9 (64.3%) | 10 (100.0%) | 0.053 |
| Greater quadriceps weakness compared with ileopsoas muscle | 0 (0.0%) | 5 (50.0%) | 0.006 |
| Finger flexor muscles weaker than deltoid muscle | 4 (28.5%) | 9(90%) | 0.004 |
| Quadriceps or finger flexor muscles atrophy | 5 (35.7%) | 10 (100.0%) | 0.002 |
| Asymmetric muscle weakness in physical exam | 3 (21.4%) | 8 (80.0%) | 0.011 |
| Fist sign | 3 (21.4%) | 8 (80.0%) | 0.011 |
| Oligosymptomatic phenotype | 4 (28.6%) | 0 (0.0%) | 0.114 |
| Proximal muscle weakness phenotype | 5 (35.7%) | 1 (10.0%) | 0.340 |
| Proeminent quadríceps or finger flexor muscles weakness phenotype | 4 (28.6%) | 9 (90.0%) | 0.004 |
| Diffuse muscle weakness phenotype | 1 (7.1%) | 0 (0.0%) | >0.999 |
a
n (%).
b
Chi-square; Fisher’s exact test.