Table 3.

Histological changes in muscles biopsies of patients with inflammatory myopathies with mitochondrial pathology (IM-Mito) and inclusion body myositis (IBM).

N	Group	Dystrophic pattern	Vacuoles	Inflammation	COX-	CD68/CD8/MHC-I	TDP-43/p62
1	IM-Mito	−	A	++	3%	++/++/+	A/A
2	IM-Mito	+	A	++	1%	++/+/++	P/A
3	IM-Mito	−	A	+	1%	++/+/+	A/A
4	IM-Mito	+	A	++	10%	++/+/++	A/A
5	IM-Mito	−	A	+	1%	+/+/+	A/A
6	IM-Mito	−	A	++	1%	+/+/+	A/P
10	IM-Mito	+	A	++	1%	++/+/++	A/A
16	IM-Mito	−	A	+	1%	+/+/+++	A/A
17	IM-Mito	+	A	+++	1%	++/++/+++	A/P
18	IM-Mito	−	A	+	1%	+/+/++	A/A
20	IM-Mito	+	A	++	2%	+/+/+++	A/A
22	IM-Mito	+	A	++	3%	++/++/+++	A/P
23	IM-Mito	+	A	+	10%	+/+/+++	A/A
24	IM-Mito	+	A	+	5%	++/+/++	A/A
7	IBM	+++	P	+++	10%	+++/+++/++	P/P
8	IBM	+	P	++	5%	++/++/+++	A/A
9	IBM	+	P	++	1%	+++/+++/++	P/P
11	IBM	++	P	+	1%	+/+/+	P/P
12	IBM	+	P	+++	2%	+++/+++/++	A/P
13	IBM	++	P	++	1%	++/++/+++	P/P
14	IBM	+	P	++	1%	++/++/++	A/P
15	IBM	++	P	++	5%	++/++/+++	P/P
19	IBM	+	P	++	1%	++/++/++	A/A
21	IBM	+	P	++	7%	++/++/++	A/A

A, absent; P, present; −, no change; +, mild; ++, moderate; +++, severe.