Table 2. Comparison of immediate reactions with different BTR severity grade. We analyzed 689 immediate reactions; 2 reactions were excluded, because the severity was unknown.
| Parameter | Mild BTRs (n=586) | Moderate/severe BTRs (n=103) | Significance (P value) |
|---|---|---|---|
| Sex, n (%) | 0.71 | ||
| Male | 279 (47.6) | 47 (45.6) | |
| Female | 307 (52.4) | 56 (54.4) | |
| Index severity, n (%) | <0.001 | ||
| Mild | 528 (90.1) | 55 (53.4) | |
| Moderate | 39 (6.7) | 29 (28.2) | |
| Severe | 5 (0.9) | 13 (12.6) | |
| Unknown | 14 (2.4) | 6 (5.8) | |
| Premedication, n (%) | <0.001 | ||
| H1-blocker + corticosteroid | 154 (26.3) | 58 (56.3) | |
| H1-blocker | 429 (73.2) | 44 (42.7) | |
| Corticosteroid | 3 (0.5) | 1 (1) |
The data is presented as number of BTRs in the examined subgroup and in blankets the frequency compared to the total number of examined BTRs in the column (mild BTRs versus moderate/severe BTRs). BTR, breakthrough reaction.