Table 3. Comparison of immediate reactions with mild index severity grade. We analyzed 583 immediate reactions with a mild index reaction compared to the severity of the BTR.
| Parameter | Mild index to moderate/severe BTRs | Mild index to mild BTRs | Statistical significance (P value) |
|---|---|---|---|
| Number | 55 | 528 | |
| Male:female (ratio) | 25:30 (1:1.2) | 248:280 (1:1.129) | 0.83 |
| Age, years | 55.91±11.7 | 54.51±11.9 | 0.88 |
| Index compared to which BTR | 0.93 | ||
| First BTR | 33 (60) | 329 (62.3) | |
| Second BTR | 11 (20) | 99 (18.8) | |
| Third BTR | 3 (5.5) | 44 (8.3) | |
| Fourth BTR | 4 (7.3) | 24 (4.5) | |
| Fifth BTR | 0 (0) | 17 (3.2) | |
| Sixth BTR | 1 (1.8) | 8 (1.5) | |
| Seventh BTR | 1 (1.8) | 2 (0.4) | |
| Eighth BTR | 1 (1.8) | 2 (0.4) | |
| Ninth BTR | 0 (0) | 2 (0.4) | |
| Tenth BTR | 1 (1.8) | 1 (0.2) | |
| CM-change | 0.21 | ||
| ICM-change | 39 (70.9) | 384 (72.7) | |
| No-ICM-change | 12 (21.8) | 129 (24.4) | |
| Unknown | 4 (7.3) | 15 (2.8) | |
| Premedication | <0.01 | ||
| H1-blocker | 31 (56.4) | 400 (75.8) | |
| H1-blocker + corticosteroid | 23 (41.8) | 125 (23.7) | |
| Corticosteroid | 1 (1.8) | 3 (0.6) |
Data are presented as n (% or ratio) or mean ± standard deviation. The data is presented as number of BTRs in the examined subgroup and in brackets the frequency compared to the total number of examined BTRs in the column (mild index to moderate/severe BTRs versus mild index to mild BTRs). BTR, breakthrough reaction; ICM, iodinated contrast media.