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Time on the timed-up and go test between baseline and 1-year visit per quintile of WMH volume (%ICV) change over 1 year. Q1 is greatest WMH volume reduction and Q5 represents the greatest WMH increase. BL: Baseline; ICV: Intracranial volume; Q: Quintile; TUG: Timed- Up and Go; WMH: White matter hyperintensity.
