Table 1.
Demographic characteristics of the mild stroke study 3 participants attending baseline and 1 year visit
| N | Baseline | N | 1 year | |
|---|---|---|---|---|
| Age, mean (SD) | 229 | 65.85 (11.13) | 215 | 66.79 (11.18) |
| Sex, male (%) | 229 | 152 (66) | 215 | 143 (62) |
| Index stroke subtype, N (%) | 229 | 215 | ||
| Subcortical | 130 (57) | 124 (58) | ||
| Cortical | 99 (43) | 91 (42) | ||
| Brain side affected by index stroke, n (%) | 229 | 215 | ||
| Right | 105 (45.9) | 100 (46.5) | ||
| Left | 93 (40.6) | 85 (39.5) | ||
| Both | 16 (7.0) | 16 (7.4) | ||
| Not visible | 15 (6.6) | 14 (6.5) | ||
| Handedness, N (%) | 229 | 215 | ||
| Right | 211 (92) | 198 (92) | ||
| Left | 16 (7) | 15 (7) | ||
| Both | 2 (1) | 2 (1) | ||
| TIA or stroke before index stroke, yes (%) | 229 | 36 (16) | - | - |
| TIA or stroke since baseline, yes (%) | - | - | 228 | 13 (5.7) |
| Incidental DWI + lesion since stroke diagnosis, yes (%) | - | - | 228 | 52 (22.8) |
| Hypertension, yes (%) | 229 | 157 (69) | 215 | 151 (70) |
| Hypercholesterolemia, yes (%) | 229 | 171 (75) | 215 | 160 (74) |
| History of smoking, yes (%) | 229 | 44 (19) | 215 | 35 (16) |
| Diabetes mellitus, yes (%) | 229 | 50 (22) | 215 | 47 (22) |
| VRF combined score (%) | 229 | 215 | ||
| 0 | 21 (9) | 20 (9) | ||
| 1 | 57 (25) | 52 (24) | ||
| 2 | 94 (41) | 90 (42) | ||
| 3 | 51 (22) | 49 (23) | ||
| 4 | 6 (3) | 4 (2) | ||
| mRS, median (IQR), range | 229 | 1 (1–1), 0–2 | 215 | 1 (0–1) 0–3 |
| NIHSS, median (IQR), range | 229 | 1 (0–2), 0–7 | 208 | 1 (0–2) 0–7 |
| TUG time (seconds), mean (SD) | 225 | 12.61 (6.28) | 206 | 12.30 (5.51) |
| 9HPT dominant hand (seconds), mean (SD) | 222 | 15.90 (5.78) | 207 | 16.70 (5.39) |
| 9HPT non-dominant hand (seconds), mean (SD) | 222 | 17.65 (6.87) | 207 | 18.68 (8.16) |
| MoCA total score, mean (SD) | 220 | 25.05 (3.48) | 198 | 25.83 (3.57) |
| NART (total errors), mean (SD) | 225 | 17.37 (9.53) | - | - |
| SIS—mobility (max. 45), median (IQR) | - | - | 195 | 44 (38–45) |
| SIS—hand function (max. 25), median (IQR) | - | - | 179 | 25 (21–25) |
| SIS—recovery (max. 100, i.e. full recovery), median (IQR) | - | - | 197 | 90 (75–95) |
| Fazekas score periventricular WMH (%) | 228 | 203 | ||
| 0 | 8 (3.5) | 11 (5.4) | ||
| 1 | 111 (48.7) | 91 (44.8) | ||
| 2 | 59 (25.9) | 55 (27.1) | ||
| 3 | 50 (21.9) | 46 (22.7) | ||
| Fazekas score deep WMH (%) | 228 | 203 | ||
| 0 | 21 (9.2) | 20 (9.9) | ||
| 1 | 122 (53.5) | 110 (54.2) | ||
| 2 | 59 (25.9) | 45 (22.2) | ||
| 3 | 26 (11.4) | 28 (13.8) | ||
| WMH volume (ml), mean (SD) | 228 | 14.93 (18.19) | 203 | 16.55 (20.59) |
| WMH volume (%ICV), mean (SD) | 228 | 0.934 (1.122) | 203 | 1.032 (1.266) |
9HPT, 9 hole peg test; DWI+, Diffusion weighted imaging positive; ICV, Intracranial volume; IQR, Interquartile range; MoCA, Montreal Cognitive Assessment; mRS, Modified Rankin Score; NART, National Adult Reading Test; NIHSS, National Institutes of Health Stroke Scale; SD, Standard Deviation; SIS, Stroke impact scale; TIA, Transient Ischaemic Attack; TUG, Timed-up and go; VRF, Vascular risk factors; WMH, White matter hyperintensity.