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. 2024 May 6;7(5):e249840. doi: 10.1001/jamanetworkopen.2024.9840

Figure 1. Genomic Profiling for KRAS Allelic Variants in Biliary Tract Cancers.

Figure 1.

A, Extrahepatic cholangiocarcinoma (EHCC) and perihilar cholangiocarcinoma (PHCC) had the highest prevalence of KRAS allelic variants. B, KRAS copy number alterations and counts were obtained from The American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange. C, G12D and G12V composed the majority of KRAS allelic variants in biliary tract cancer. GBC indicates gallbladder cancer; IHCC, intrahepatic cholangiocarcinoma; VUS, variant of uncertain significance.