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. 2000 Sep 15;28(18):3452–3461. doi: 10.1093/nar/28.18.3452

Figure 7.

Figure 7

Conservation of 5′ ETS structural elements. Imperfect inverted repeats in equivalent positions of aligned 5′ ETS sequences (not shown) suggest the presence of secondary structures in C.fasciculata and Leishmania species. The L.donovani sequence (17), which is very similar to the other Leishmania sequences, was used in this figure. Structure 1 spans C.fasciculata IGS positions 2883–2953 (ETS positions 429–499); structure 2 encompasses C.fasciculata IGS positions 3191–3230 (ETS positions 737–776); structure 3 begins at C.fasciculata IGS position 3370 (ETS position 916) and ends 4 nt into the 5′ end of the SSU rRNA sequence. Arrows indicate the positions of processing sites (A0 and A1). The L.donovani structure 1 spans ETS positions 411–489, which are obviously similar to the sequence used in the C.fasciculata structure. The L.donovani structure 2 sequence (ETS positions 750–781) is not very similar to the corresponding C.fasciculata sequence; however, in both organisms this sequence follows shortly after the conserved sequence presented in Figure 6B and is immediately followed by another short stretch of sequence that is conserved between the two organisms. The L.donovani structure 3 begins at ETS position 922.