Figure 1.

Disease severity and MuSK IgG levels were reduced after immunosuppression. (A) MGFA scores of patients with MuSK-MG at onset and at follow-up time after receiving immunosuppression. ****p < 0.0001, Wilcoxon matched-pair signed-rank test. To increase visibility, the lines of the MGFA scores were nudged slightly up or down. (B) MuSK IgG levels (determined at the time of diagnosis and the last follow-up) were reduced after receiving immunosuppressive treatment. Wilcoxon matched-pair signed-rank test, ****p < 0.0001. Comparison of (C) MGFA scores and (D) MuSK IgG titers (nM) before and after distinct treatments. Treatment is indicated as follows: blue = prednisone or dexamethasone, green = prednisone in combination with azathioprine, and pink = prednisone in combination with IVIG, cyclophosphamide, plasmapheresis, or mycophenolate mofetil. Kruskal–Wallis with Dunn’s post test. ****p < 0.0001, **p = 0.0013, *p = 0.0103. To include samples from patients with clinical remission in the graphs, these were given a value of “MGFA = 0”.