Figure 6.

Serum IgG4 concentrations in patients with MG were, with a few exceptions, within the normal range, while relative IgG4 levels (IgG4/IgG) were enriched in patients with AChR-MG and MuSK-MG. (A) IgG4 serum concentrations in patients with MG and controls, Kruskal-Wallis test with Dunn’s multiple comparisons test. The dotted line indicates the cut-off for elevated IgG4 levels (defined as 1.35 g/L). (B) Relative IgG4 levels (IgG4/IgG), Kruskal–Wallis test with Dunn’s multiple comparisons test. **Non-disease controls vs. MuSK-MG untreated: p = 0.0038; ***non-disease controls vs. MuSK treated: p = 0.0002; **non-disease controls vs. AChR-MG treated: p = 0.0051. ns= non-significant.