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. Author manuscript; available in PMC: 2024 May 7.
Published in final edited form as: J Immunol. 2022 Feb 18;208(6):1406–1416. doi: 10.4049/jimmunol.2100900

Figure 2. Pro-inflammatory cytokines in the lung in response to BCG/αIL-10R1 administration.

Figure 2.

WT mice were immunized with BCG/αIL-10R1 or BCG/IgG1 antibody subcutaneously. Immunized mice were euthanized at 1- and 7-weeks post immunization. Lungs were homogenized and centrifuged to obtain clarified homogenate. IFN-γ (A), TNF-α (B) IL-17 (C) and IL-12p70 (D) were measured by ELISA. Data represent the mean ± SE of one of two independent experiments with 3–5 mice in each group at each time point. Saline group is pooled data of mice (n=4) from 1- and 7- weeks post immunization. Student’s t test was performed to determine statistical significance between the BCG/IgG1 and BCG/αIL-10R1 experimental groups at 1- and 7-weeks post vaccination. *P<0.05; **P<0.01.