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. 2023 Aug 4;27(2):83–90. doi: 10.1016/j.cjtee.2023.08.001

Table 5.

Comparison of coagulation dysfunction among patients stratified by heatstroke and heatstroke-induced coagulopathy.

Characteristics Non-heatstroke group (n = 171) Heatstroke groups
Z/χ2 p value
Non-HIC group (n = 95) HIC group (n = 36)
Platelet count (1 × 109/L) 194 (165, 226) 202 (158, 236) 105 (51, 178) ab 34.351 < 0.001
PT (sec) 12.6 (11.9, 13.5) 13.3 (12.4, 14.3)a 19.8 (17.0, 27.5) ab 75.718 < 0.001
INR 1.06 (0.98, 1.14) 1.12 (1.07, 1.22)a 1.71 (1.41, 2.26) ab 85.062 < 0.001
APTT (sec) 29.8 (26.8, 32.8) 29.9 (26.5, 32.9) 39.7 (28.3, 58.6) ab 23.203 < 0.001
Fibrinogen (g/L) 2.4 (2.0, 2.8) 2.3 (1.9, 2.7) 1.7 (1.2, 2.3) ab 21.496 < 0.001
D-dimer (μg/mL) 0.2 (0.1, 0.5) 0.5 (0.2, 0.9)a 3.6 (2.4, 8.1) ab 85.815 < 0.001
HIC score 0 (0, 0) 1 (0, 1)a 4 (3, 5) ab 141.667 < 0.001
In-hospital mortality (%) 0 (0) 0(0) 7 (19.4) 31.072 < 0.001

Values are median (Q1, Q3), unless otherwise indicated.

ap < 0.05 compared with the non-heatstroke group.

bp < 0.05 compared with the non-HIC group.

PT: prothrombin time; INR: international normalized ratio; APTT: activated partial thromboplastin time; HIC: heatstroke-induced coagulopathy.