Table 2.

Distribution of hypogammaglobulinemia at diagnosis.

Immunoglobulin	IVIG (n = 56)	Non-IVIG (n = 33)	p-value
IgG, n (%)	9 (16.1)	3 (9.1)	0.542
IgA, n (%)	4 (7.1)	3 (9.1)	1.000
IgM, n (%)	34 (60.7)	17 (51.5)	0.701
IgD, n (%)	29 (51.8)	16 (48.5)	0.421

IgA, immunoglobulin A; IgD, immunoglobulin D; IgG, immunoglobulin G; IgM, immunoglobulin M; IVIG, intravenous immunoglobulin.

In the IVIG group, 16 patients demonstrated overlapped hypogammaglobulinemia, and in the non-IVIG group, five patients had overlapped hypogammaglobulinemia.