Table 31.
Spinal epidural lipomatosis presenting with low back paina
| Author / year / country | Design / setting | Patient(s) | Spinal symptoms | Diagnostic confirmation |
|---|---|---|---|---|
| Chan et al., 2009, Taiwan [471] | CR / hospital outpatient depart-ment | male, 56 y, BMI: 24.1 kg/m2 | chronic LBP (sustained, worsening), left leg weakness and numbness, inability to walk long distances | MRI |
| male, 44 y, BMI 23.4 kg/m2 | chronic LBP (progressive worsening, inability to walk for long distances), left extremity weakness and numbness | MRI | ||
| Duran et al., 2016, Turkey [474] | CR / not reported | female, 46 y, BMI: 32 kg/m2 | chronic LBP (exacerbating over three months, deep, sharp), radicular pain in the proximal leg | MRI |
| Min et al., 2007, South Korea [475] | CR / not reported | male, 70 y, BMI: normal | chronic LBP (VAS 8/10, aggravating by standing and walking, relieved by sitting and leaning forward during walking), radiating to both lower limbs. | MRI |
| McCormick et al., 2014, USA [476] | CR / hospital | male, 79 y, BMI: 42.1 kg/m2 | chronic LBP (progressive, VAS 8/10, stabbing, relieved by sustained lumbar flexion positions and exacerbated by walking or standing), radiation to the right anterolateral thigh | MRI |
| male, 47 y, BMI: 32.5 kg/m2 | chronic LBP (VAS 9/10, burning and tingling, exacerbated by sitting, standing, and walking), radiation to anterolateral thigh and lateral posterior leg | MRI | ||
| male, 50 y, BMI: 48 kg/m2 | acute LBP (severe, VAS 10/10, achy and numb, began upon standing from a seated position, patient felt a “pop”, exacerbated by standing, walking, and ascending stairs) | MRI | ||
| Al-Khawaja et al., 2008, Australia [473] | CR / not reported | male, 68 y, BMI: not reported | chronic LBP (aggravating by standing longer than 10 minutes or walking greater than 200 m), claudication right anterior thigh and lateral lower leg | MRI |
| Botwin et al., 2004, USA [477] | CR / not reported | female, 78 y, BMI: 28.2 kg/m2 | chronic LBP (VAS 8/10, aggravated by standing and walking, relieved by sitting and leaning forward), radiation to the left lower limb | MRI |
| male, 68 y, BMI: 32.6 kg/m2 | chronic LBP (VAS 8/10, aggravated by standing and walking, relieved by sitting and leaning forward during walking), radiation to the right lower limb | MRI | ||
| Choi et al., 2012, Korea [478] | CR / not reported | male, 67 y, BMI: 25.5 kg/m2 | back pain (no duration or localisation reported), leg tightness in both legs, neurogenic claudication | MRI, MR myelogram |
| Lisai et al., 2001, Italy [479] | CR / not reported | male, 67 y, BMI: not reported | chronic LBP, bilateral pain radiating to his feet | CT / MRI |
| male, 54 y, BMI: not reported | chronic LBP, radiating pain in both legs and intermittent sacral nerve dysfunction including penile erection, incontinence, perineal pain | MRI | ||
| Maillot et al., 2006, France [480] | CR / hospital | male, 63 y, BMI: 32.6 kg/m2 | chronic LBP (diurnal on standing and walking, walking limited to 200 m), pain in lower limbs, radicular pain in the left calf | CT myelography |
| Borré et al., 2003, Argentina [470] | CS / hospital | 2528 (57% female), mean age: 47.3 y | non-specific LBP (no duration reported) (LEL grade I: 0%; LEL grade II: up to 14.5%; LEL grade III: up to 100%); radicular pain, numbness and dysaesthesias, neurogenic claudication, cauda equina syndrome; LEL grade I: no symptomatic patients; LEL grade II: 14.5% were symptomatic with weakness and / or dysaesthesia (no other substantial pathologic findings in MRIs); LEL grade III: 100% were symptomatic, 42.3% showed other pathological findings | - |
| Ishikawa et al., 2006, Japan [472] | CHS / hospital | 7 (29% female), mean age: 65.7 y, mean BMI: 27.1 kg/m2 | LBP (queried) (no duration reported), neurological deficits in the lower extremities, with intermittent claudication as seen in cauda equina syndrome | - |
| Al-Khawaja et al., 2008, Australia [473] | NR / - |
111 cases: 44% idiopathic: 10% female, 70% obese, mean age: 46 y 56% secondary: 20% female, 70% obese, mean age: 44 y |
idiopathic lumbar lipomatosis: 65% back (no duration or localisation reported) or leg pain, 30% leg weakness, 30% claudication; secondary lumbar lipomatosis: 50% back (no duration or localisation reported) or leg pain, 25% leg weakness, 10% claudication |
- |
ain all publications no extraspinal symptoms were reported
BMI body mass index, CHS cohort study, CR case report, CS case series, CT computed tomography, LBP low back pain, LEL lumbosacral epidural lipomatosis, MR magnetic resonance, MRI magnetic resonance imaging, NR narrative review, VAS visual analogue scale, y years