Table 3.
Clinicopathological factors of patients with and without a temporary stoma closure
| Stoma Closure | Stoma Non-closure | P value | |
|---|---|---|---|
| Case number | 853 | 103 | |
| Age (Std. dev) | 61.2 (12.5) | 64.5 (13.4) | 0.014 |
| Sex (%) | 0.277 | ||
| M | 576 (67.5) | 75 (72.8) | |
| F | 277 (32.5) | 28 (27.2) | |
| BMI (Std. dev) | 24.3 (3.4) | 24.3 (4.0) | 0.932 |
| eGFR ≤ 30 mL/min/1.73m2(%) | 15 (1.8) | 9 (8.7) | < 0.001 |
| Anastomosis leakage | 76 (8.9) | 22 (21.4) | < 0.001 |
| Stomy timing | 0.750 | ||
| Primary | 794 (93.1) | 95 (92.2) | |
| After leakage | 59 (6.9) | 8 (7.8) | |
| Stoma type | 0.494 | ||
| Ileostomy | 135 (15.8) | 19 (18.4) | |
| Colostomy | 718 (84.2) | 84 (81.6) | |
| CVA (%) | 23 (2.7) | 6 (5.8) | 0.08 |
| Liver cirrhosis (%) | 11 (1.3) | 3 (2.9) | 0.195 |
| T stage (%) | 0.005 | ||
| 0–2 | 265 (31.1) | 19 (18.4) | |
| 3 | 533 (62.5) | 71 (68.9) | |
| 4 | 55 (6.4) | 13 (12.6) | |
| N stage (%) | 0.001 | ||
| 0 | 482 (56.5) | 42 (40.8) | |
| 1 | 233 (27.3) | 30 (29.1) | |
| 2 | 138 (16.2) | 31 (30.1) | |
| Low rectal tumor (%) | 354 (41.5) | 46 (44.7) | 0.539 |
| Involved circumferential margin (%) | 258 (30.3) | 51 (49.5) | < 0.001 |
| Laparoscopy (%) | 281 (32.9) | 27 (26.2) | 0.167 |
| Albumin < 3.5 g/dL (%) | 48 (5.6) | 10 (9.7) | 0.101 |
| CEA > 5 ng/mL | 183 (21.5) | 40 (38.8) | < 0.001 |
| Neoadjuvant RTa (%) | 261 (30.6) | 25 (24.3) | 0.185 |
| Adjuvant chemotherapy | 260 (30.5) | 19 (18.4) | 0.011 |
| Chemotherapy with Oxaliplatinb | 54 (20.8) | 8 (42.1) | 0.031 |
BMI body mass index, eGFR estimated Glomerular filtration rate, CVA Cerebrovascular accident, CEA carcinoembryonic antigen, RT radiotherapy
aIncluding both long-course and short-course radiation therapy
bPercentage of chemotherapy patients