Fig 7.

Resveratrol inhibits bacterial invasion of the bladder mucosa. Adult female CBA/JCrHsd mice were inoculated via trans-urethral catheterization with 10⁷ CFU of UTI89 suspended in PBS containing either DMSO or resveratrol (300 µM). Bladders were extracted 1 h later, and the numbers of intracellular, gentamicin-protected bacteria were determined. Bars indicate median values; n = 11 mice from two independent experiments. P value determined using the Mann-Whitney U test.