Figure 2. Percentages of Amino Acid Composition in Previous CEST Reports Compared to New Synthetic CEST Reporters.

(a) The bar graph shows each amino acid’s portion of the total protein as a percentage. A specific color displays each reporter: orange representing LRP8, yellow representing rdLRP10,35, green representing hPRM115, and red representing superCESTide. (b) The bar graph shows each amino acid group’s portion of the total protein as a percentage. Amino acids were grouped based on the properties of their associated side chains. Each reporter is displayed by a specific color, with orange representing LRP, yellow representing rdLRP, green representing hPRM1, and red representing superCESTide. (c) Predicted structure of superCESTide generated by FoldX and displayed in PyMOL.