Table 3.
Number (%) | Univariable Analysis | Multivariable Analysis | |||||
---|---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | ||||
Sex | Female | 1945 (77.52%) | 1.60 (1.28, 2.01) | <0.0001 | 1.06 (0.80, 1.41) | 0.677 | |
Age | >30 | 1899 (75.69%) | 0.57 (0.44, 0.74) | <0.0001 | 0.69 (0.53, 0.91) | 0.009 | |
Job category | AS | 312 (12.44%) | 1.0 | ||||
LP | 608 (24.23%) | 1.17 (0.85, 1.61) | 0.3376 | 1.08 (0.76, 1.53) | 0.685 | ||
MS | 253 (10.08%) | 0.99 (0.67, 1.45) | 0.9516 | 0.96 (0.64, 1.42) | 0.821 | ||
Nurse | 1336 (53.25%) | 1.95 (1.45, 2.63) | <0.0001 | 1.54 (1.09, 2.19) | 0.015 | ||
TSH (μIU/mL) | Within normal range (0.56–5.91) | 2338 (93.18%) | 1.0 | ||||
Subpar to normal range (≤0.56) | 63 (2.51%) | 0.66 (0.37, 1.18) | 0.1640 | ||||
Superior to normal range (≥5.91) | 108 (4.30%) | 1.13 (0.67, 1.89) | 0.6428 | ||||
FT3 (pg/mL) | Within normal range (2.30–4.80) | 2471 (98.49%) | 1.0 | ||||
Superior to normal range (≥4.80) | 38 (1.51%) | 1.51 (0.59, 3.89) | 0.3934 | ||||
FT4 (ng/dL) | Within normal range (0.59–1.25) | 2473 (98.57%) | 1.0 | ||||
Subpar to normal range (≤0.59) | 22 (0.88%) | 0.48 (0.20, 1.19) | 0.1130 | ||||
Superior to normal range (≥1.25) | 14 (0.56%) | 0.56 (0.18, 1.80) | 0.3321 | ||||
BMI (kg/m2) | 18–24 | 1520 (60.58%) | 1.0 | ||||
<18 | 86 (3.43%) | 2.69 (1.16, 6.23) | 0.0211 | 2.39 (1.02, 5.58) | 0.045 | ||
>24 | 903 (35.99%) | 0.69 (0.56, 0.85) | 0.0004 | 0.87 (0.69, 1.10) | 0.238 | ||
Hypertension | 704 (28.06%) | 0.77 (0.62, 0.96) | 0.0191 | ||||
LDL-C (mmol/L) | Within normal range (<3.37) | 1921 (76.56%) | 1.0 | ||||
Superior to normal range (≥3.37) | 588 (23.44%) | 0.72 (0.58, 0.91) | 0.0054 | 1.08 (0.73, 1.59) | 0.695 | ||
HDL-C (mmol/L) | Within normal range (1.03–1.55) | 1667 (66.44%) | 1.0 | ||||
Subpar to normal range (≤1.03) | 219 (8.73%) | 0.83 (0.58, 1.17) | 0.2785 | ||||
Superior to normal range (≥1.55) | 623 (24.83%) | 1.04 (0.82, 1.32) | 0.7411 | ||||
UA (μmol/L) | Within normal range (208–428) | 2243 (89.40%) | 1.0 | ||||
Subpar to normal range (≤208) | 36 (1.43%) | 0.86 (0.38, 1.99) | 0.7304 | 0.80 (0.34, 1.87) | 0.610 | ||
Superior to normal range (≥428) | 230 (9.17%) | 0.47 (0.35, 0.63) | <0.0001 | 0.56 (0.41, 0.78) | 0.001 | ||
CHO (mmol/L) | Within normal range (3.25–5.2) | 1895 (75.53%) | 1.0 | ||||
Subpar to normal range (≤3.25) | 78 (3.11%) | 0.64 (0.38, 1.09) | 0.0998 | 0.60 (0.35, 1.04) | 0.066 | ||
Superior to normal range (≥5.2) | 536 (21.36%) | 0.70 (0.55, 0.88) | 0.0029 | 0.82 (0.56, 1.20) | 0.303 | ||
TG (mmol/L) | Within normal range (≤1.7) | 2113 (84.22%) | 1.0 | ||||
Superior to normal range (>1.7) | 396 (15.78%) | 0.91 (0.70, 1.20) | 0.5162 | ||||
Glc (mmol/L) | Within normal range (3.9-6-1) | 2418 (96.37%) | 1.0 | ||||
Subpar to normal range (≤3.9) | 32 (1.28%) | 0.98 (0.40, 2.40) | 0.9648 | ||||
Superior to normal range (≥6.1) | 59 (2.35%) | 0.80 (0.43, 1.49) | 0.4842 | ||||
Surgical relevant work | 915 (36.47%) | 1.40 (1.13, 1.74) | 0.0024 | 1.19 (0.93, 1.53) | 0.155 | ||
Radiation exposure | 213 (8.49%) | 0.84 (0.59, 1.18) | 0.3091 | 1.09 (0.75, 1.58) | 0.660 |
Note: Vitamin D deficiency is defined as 25(OH)D < 12.3ng/mL.
Abbreviations: AS, Administrative staff; LP, Licensed physicians; MS, Medical scientists; TSH, thyroid stimulating hormone; FT3, free thyroxine 3; FT4, free thyroxine 4; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; UA, uric acid; CHO, cholesterol; TG, triacylglycerol; Glc, glucose.