Figure 2.
Schematic illustrating the timescales observed in the experiments. The key time points include radiation on and off times (t ron and t roff) and bubble onset time (t bo). The time courses include irradiation time (t rad) and the time before and after bubble onset (t bbo and t abo). Bubbles that emerged sequentially (using round ones as examples) are indicated with different colors to distinguish from one another. The in-line phase-contrast radiographs in (b) each have a field of view of 50 mm (width) by 4 mm (height). Frame 0 shows the lung tissue context in a static radiograph, while frames 1–4 are cineradiographs at different time points after bubble onset and subtraction of the tissue context. All images in (b) are obtained after context-specific flat-field corrections (see SI Section S2). (c) Quantification of the global bubble evolution using their time-dependent volume within the field of view and (d) the cumulative volume. The temporal locations of the frames in (b) are indicated in (c) and (d) as vertical dashed lines.