Fig 4. Neutralization antibodies from C57BL/6 mice vaccinated with V5040 or CHIKV 181/25.

Antisera collected from terminal bleeding of mice vaccinated either with V5040 or CHIKV 181/25 were tested for PRNT₅₀ assays against their corresponding homologous virus. Blue circles and red squares indicate antisera of CHIKV 181/25 and V5040, and each symbol represents serum from an individual mouse (n = 8/group/timepoint). The bar and whiskers indicate the means and ± their standard deviation. Ns: not significant. **, P < 0.0021, Two-Way ANOVA with Sidak’s multiple comparisons test (Prism).