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. 2000 Oct 1;28(19):3771–3778. doi: 10.1093/nar/28.19.3771

Table 2. Rates at which selectable phenotypes are generated in ERCC1+ and ERCC1 cells.

Selection Rates (×10–7)
  ERCC1+   ERCC1  
  GS22-15a AK784b GS22-13a GSAK1b
TKAPRT 1.4 ± 0.5 1.1 6 ± 3 1.8
TK 15 ± 3 17 48 ± 23 62
APRT 14 ± 3 6.9 31 ± 25 42

aData for GS22-13 and GS22-15 are from Sargent et al. (19). GS22-13 and GS22-15 have tandem duplications identical to AK784 and GSAK1 except that they do not carry the 800 bp segment of non-homology or an I-SceI site in the second intron of APRT.

bData for AK784 and GSAK1 are from a single 12 pot fluctuation experiment analyzed to determine recombination rates, as described previously (23,24).