Table 4.

Hazard ratios for the different dipping categories and reaching different outcomes among CRIC cohort participants with prior CVD Adjusted for Age, BMI, Sex, Diabetes, Race, eGFR, Urine Protein to Creatinine Ratio, Clinic SBP.

		Unadjusted model			Adjusted model
Outcome	Dipping category	Hazard ratio	95% CI	p-value	Hazard ratio	95% CI	p-value
Composite renal outcome	Dipper	Reference
	Non-dipper	1.63	1.14–2.34	0.008	1.16	0.77–1.74	0.482
	Reverse dipper	2.06	1.39–3.07	<0.001	1.56	1.00–2.42	0.049
ESRD	Dipper	Reference
	Non-dipper	1.79	1.19–2.72	0.006	0.99	0.61–1.60	0.961
	Reverse dipper	2.05	1.30–3.25	0.002	1.37	0.83–2.28	0.222
All-cause death	Dipper	Reference
	Non-dipper	1.01	0.75–1.34	0.995	0.8	0.58–1.10	0.163
	Reverse dipper	1.48	1.09–2.02	0.012	1.03	0.73–1.46	0.869
Cardiovascular death	Dipper	Reference
	Non-dipper	1.06	0.59–1.92	0.843	1.08	0.58–2.00	0.81
	Reverse dipper	1.66	0.90–3.07	0.104	1.3	0.65–2.58	0.462
Composite CV outcome	Dipper	Reference
	Non-dipper	0.93	0.69–1.25	0.616	0.81	0.56–1.12	0.195
	Reverse dipper	1.18	0.85–1.64	0.337	0.88	0.61–1.29	0.521

DR dipping ratio, CV cardiovascular, CVD cardiovascular disease, ESRD end-stage renal disease.