Fig. 6. tauFisher incorporated with bootstrapping suggests that the circadian phases in dermal immune cells are more heterogeneous than in dermal fibroblasts.

a A general overview of the pipeline that incorporates tauFisher with bootstrapping. b Radar plots showing the distribution of the prediction outcome for 500 pseudobulk replicates from dermal fibroblasts (red) and immune cells (blue). c Bar plots showing the differences between the prediction mean (left) and standard deviation (right) at each ZT (immune cells - fibroblasts). ****p-value ≤ 0.0001. P-values are determined using Rao’s Tests for Homogeneity and the Wallraff Test of Angular Distances. Source data and exact p-values are provided as a Source Data file.