TABLE 1.

Mean values and standard deviations of the proteins in controls (C) and bipolar disorder (BD) patients.

Parameter	C (N = 20)	BD patients (N = 20)	p-value
Age (years)	48.80 ± 7.34	51.10 ± 9.85	0.408 a
Gender (F/M)	10/10	10/10	-
IGF-2 (ng/mL)	114.53 ± 50.59	135.25 ± 64.02	0.478 b
IGFBP-1 (ng/mL)	8.17 ± 4.78	8.92 ± 4.06	0.597 a
IGFBP-3 (ng/mL)	474.33 ± 82.24	264.11 ± 60.22	< 0.0001 a
IGFBP-5 (ng/mL)	82.46 ± 14.77	33.35 ± 13.06	< 0.0001 a
IGFBP-7 (ng/mL)	70.09 ± 28.89	143.21 ± 130.69	0.165 b
MCP-1 (pg/mL)	72.31 ± 27.18	109.33 ± 73.92	< 0.05 a
MIP-1β (pg/mL)	43.59 ± 23.66	80.52 ± 87.42	0.068 a
TNF-α (pg/mL)	36.01 ± 17.31	46.06 ± 24.64	0.150 a

The p-value was calculated and is reported according to the APA style. The following tests were applied:

^a Unpaired Student’s t-test.

^b Mann–Whitney test.

C, control group; BD, bipolar disorder; IGF, insulin-like growth factor; IGFBP, insulin-like growth factor-binding protein; MCP-1, monocyte chemoattractant protein 1; MIP-1β, macrophage inflammatory protein 1 beta; TNF-α, tumor necrosis factor alpha.