TABLE 5.
Pearson’s correlation coefficient was the main correlation coefficient used.
| Protein | YMRS | |||
|---|---|---|---|---|
| BD0 (n = 10) | BD1 (n = 10) | |||
| r | p | r | p | |
| IGF-2 (ng/mL) | −0.503 | 0.139 | 0.067 | 0.854 |
| IGFBP-1 (ng/mL) | −0.506 | 0.135 | −0.123 | 0.734 |
| IGFBP-3 (ng/mL) | 0.180 | 0.620 | 0.485 | 0.155 |
| IGFBP-5 (ng/mL) | 0.078 | 0.830 | 0.239 | 0.506 |
| IGFBP-7 (ng/mL) | −0.503s | 0.424 | 0.204 | 0.571 |
| MCP-1 (pg/mL) | 0.231s | 0.521 | −0.328 | 0.354 |
| MIP-1β (pg/mL) | −0.064 | 0.860 | −0.322s | 0.364 |
| TNF-α (pg/mL) | 0.036 | 0.921 | −0.083 | 0.820 |
r, coefficient values range from −1 to 1. sSpearman’s correlation coefficient was used when at least one of the distributions did not adjust to a normal distribution (Shapiro–Wilk test; p-value <0.05). BD0, bipolar disorder time 0 (before treatment at hospital admission in longitudinal subgroup); BD1, bipolar disorder time 1 (after treatment at hospital admission in longitudinal subgroup); IGF, insulin-like growth factor; IGFBP, insulin-like growth factor-binding protein; MCP-1, monocyte chemoattractant protein 1; MIP-1β, macrophage inflammatory protein 1 beta; TNF-α, tumor necrosis factor alpha. YMRS, Young Mania Rating Scale.