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. 2024 Apr 27;10(9):e30462. doi: 10.1016/j.heliyon.2024.e30462

Fig. 2.

Fig. 2

Anxiety- and depressive-like behaviors, serum corticosterone and pro-inflammatory cytokine levels, and GPR55 expression levels after GPR55 activation. (A) Experimental protocol. (B) Representative activity tracks in the open field test for each group. (C) Total distance in the open field test. (D) Time spent in the center area of the open field test. (E) Representative activity tracks in the elevated plus maze test. (F) Time exploring the open arms in the elevated plus maze. (G) Immobility time in the forced swim test. (H) Immobility time in the tail suspension test. (I) Serum corticosterone levels. (J–L) Serum TNF-α, IL-1β, and IL-6 levels. (M) Representative bands in Western blot analysis. (The original image is provided in the Supplementary file). (N) Relative expression levels of GPR55 protein in each group. Each group n = 9. Compared with the Vehicle group, **P < 0.01, ***P < 0.001, ****P < 0.0001; Compared with the METH group, ##P < 0.01, ###P < 0.001, ####P < 0.0001.